PALBACE (Palbociclib)

1.003.00

Palbociclib is classified as a “cyclin-dependent kinase (CDK) 4/6 inhibitor”. The drug blocks proteins in the cell called cyclin-dependent kinase (CDK) 4 and CDK 6. In hormone-positive breast cancer cells, blocking these proteins helps stop the cells from dividing to make new cells. It helps prevent the cells from moving from G1 to S cell cycle phase in the division process. This slows cancer growth.

It is used for treating certain kinds of breast cancer in women past menopause.

  • in a combination with Letrozole for the treatment of postmenopausal women with estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrine-based therapy for their metastatic disease.
  • for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)- negative advanced or metastatic breast cancer in the combination with fulvestrant in women with disease progression following endocrine therapy.

Strengths available: 75mg, 100mg & 125mg

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Additional information

Trade Name

Palbace

Generic Name

Palbociclib

Manufacturer

Pfizer

Drug Type

Oncology

Indication

Breast Cancer

Doasage Form

Capsules

Packaging

3 X 7 capsules

Strength

75mg, 100mg, 125mg